Edinburgh Clinical Toxicology - Seminal Publications

Safety and efficacy of the SNAP 12-hour acetylcysteine regimen for the treatment of paracetamol overdose. Pettie JM, Caparrotta TM, Hunter RW, Morrison EE, Wood DM, Dargan PI, Thanacoody RH, Thomas SHL, Elamin MEMO, Francis B, Webb DJ,Sandilands EA, Eddleston M, Dear JW. EClinicalMedicine 2019; 11: 11-17.

Bateman DN, Dear JW, Thanacoody HKR, Thomas SHL, Eddleston M, Sandilands EA, Coyle J, Cooper JG, Rodriguez A, Butcher I, Lewis SC, Vligenthaart ADB, Veiraiah A, Webb DJ, Gray A. Reduction of adverse effects from intravenous acetylcysteine treatment for paracetamol poisoning: a randomized controlled trial. Lancet 2014; 383: 697-704.

Proudfoot AT, Good AM, Bateman DN. Clinical toxicology in Edinburgh, two centuries of progress. Clin Toxicol 2013; 51: 509-14.

Prescott LF, Illingworth RN, Critchley JA, Stewart MJ, Adam RD, Proudfoot AT. Intravenous N-acetylcystine: the treatment of choice for acetaminophen poisoning. BMJ 1979; 2:1097–1100.

Proudfoot AT, Stewart MS, Levitt T, Widdop B. Paraquat poisoning: significance of plasma-paraquat concentrations. Lancet 1979; 18: 330-2.

Prescott LF, Park J, Ballantyne A, Adriaenssens P, Proudfoot AT. Treatment of paracetamol (acetaminophen) poisoning with N-acetylcysteine. Lancet 1977; 2: 432-4.

Prescott LF, Newton RW, Swainson CP, Wright N, Forrest AR, Matthew H. Successful treatment of severeparacetamol overdosage with cysteamine. Lancet 1974; 1: 588-92.