2014 Publications


Reduction of adverse effects from intravenous acetylcysteine treatment for paracetamol poisoning: a randomized controlled trial. Bateman DN, Dear JW, Thanacoody HKR, Thomas SHL, Eddleston M, Sandilands EA, Coyle J, Cooper JG, Rodriguez A, Butcher I, Lewis SC, Vligenthaart ADB, Veiraiah A, Webb DJ, Gray A.  Lancet 2014 Feb; 383: 697-704.


Reported toxicity in 1486 liquid detergent capsule exposures to the UK National Poisons Information Service 2009-2012, including their ophthalmic and CNS effects. Williams H, Jones S, Wood K, Scott RA, Eddleston M, Thomas SH, Thompson JP, Vale JA.  Clin Toxicol 2014 Feb; 52: 136-40.


Stratification of paracetamol overdose patients using new toxicity biomarkers: current candidates and future challenges. Dear JW, Antoine DJ. Expert Rev Clin Pharmacol. 2014 Mar;7(2):181-9.


Treatment of paracetamol overdose - authors' reply. Bateman DN, Dear JW, Thanacoody HK, Thomas SH, Eddleston M. Lancet. 2014 Apr 19;383(9926):1383.


The role of private pesticide vendors in preventing access to pesticides for self-poisoning in rural Sri Lanka. Weerasinghe M, Pearson M, Peiris R, Dawson AH, Eddleston M, Jayamanne S, Konradsen F. Injury Prevention 2014 Apr, 20: 134-7.


Increasing frequency of severe clinical toxicity after use of 2,4-dinitrophenol in the UK: a report from the National Poisons Information Service. Kamour A, George N, Gwynnette D, Cooper G, Lupton D, Eddleston M, Thompson JP, Vale JA, Thanacoody HK, Hill S, Thomas SH. Emerg Med J. 2015 May;32(5):383-6.


Guidelines for laboratory analyses for poisoned patients in the United Kingdom. Thompson J, Watson I, Thanacoody H, Morley S, Thomas S, Eddleston M, Vale J, Bateman D, Krishna C. Ann Clin Biochem 2014 May; 51: 312-25.


Retro-orbital blood acquisition facilitates circulating microRNA measurement in zebrafish with paracetamol hepatotoxicity. Vliegenthart AD, Starkey Lewis P, Tucker CS, Del Pozo J, Rider S, Antoine DJ, Dubost V, Westphal M, Moulin P, Bailey MA, Moggs JG, Goldring CE, Park BK, Dear JW. Zebrafish. 2014 Jun;11(3):219-26.


Editors: Bateman N, Jefferson R, Thomas S, Thompson J, Vale A. Oxford Desk Reference: Toxicology. Oxford University Press, June 2014. 978-0-19-959474-0.


Suicide in Sri Lanka 1975-2012: age, period and cohort analysis of police and hospital data. Knipe DW, Metcalfe C, Fernando R, Pearson M, Konradsen F, Eddleston M, Gunnell D. BMC Public Health. 2014 Aug 13;14:839.


Urinary exosomes join the fight against infection. Dear JW. J Am Soc Nephrol. 2014 Sep;25(9):1889-91.


Effect of the UK's revised paracetamol poisoning management guidelines on admissions, adverse reactions and costs of treatment. Bateman DN, Carroll R, Pettie J, Yamamoto T, Elamin ME, Peart L, Dow M, Coyle J, Cranfield KR, Hook C, Sandilands EA, Veiraiah A, Webb D, Gray A, Dargan PI, Wood DM, Thomas SH, Dear JW, Eddleston M. Br J Clin Pharmacol. 2014 Sep;78(3):610-8.


Impact of reducing the threshold for acetylcysteine treatment in acute paracetamol poisoning: the recent United Kingdom experience. Bateman DN, Dear JW, Carroll R, Pettie J, Yamamoto T, Elamin ME, Peart L, Dow M, Coyle J, Gray A, Dargan PI, Wood DM, Eddleston M, Thomas SH. Clin Toxicol (Phila). 2014 Sep-Oct;52(8):868-72.


Blood kidney injury molecule-1 is a biomarker of acute and chronic kidney injury and predicts progression to ESRD in type I diabetes. Sabbisetti VS, Waikar SS, Antoine DJ, Smiles A, Wang C, Ravisankar A, Ito K, Sharma S, Ramadesikan S, Lee M, Briskin R, De Jager PL, Ngo TT, Radlinski M, Dear JW, Park KB, Betensky R, Krolewski AS, Bonventre JV. J Am Soc Nephrol. 2014 Oct;25(10):2177-86.


Patterns of presentation and clinical features of toxicity after reported use of ([2-aminopropyl]-2,3-dihydrobenzofurans), the 'benzofuran' compounds. A report from the United Kingdom National Poisons Information Service. Kamour A, James D, Lupton DJ, Cooper G, Eddleston M, Vale A, Thompson JP, Thanacoody R, Hill SL, Thomas SH. Clin Toxicol (Phila). 2014 Dec;52(10):1025-31.


Respiratory complications of organophosphorus nerve agent and insecticide poisoning. Implications for respiratory and critical care. Hulse EJ, Davies JO, Simpson AJ, Sciuto AM, Eddleston M. Am J Respir Crit Care Med. 2014 Dec 15;190(12):1342-54.


Zebrafish as model organisms for studying drug-induced liver injury. Vliegenthart AD, Tucker CS, Del Pozo J, Dear JW. Br J Clin Pharmacol. 2014 Dec;78(6):1217-27.