2015 Publications


Taking stock: UK national antidote availability increasing, but further improvements are required. Bailey GP, Rehman B, Wind K, Wood DM, Thanacoody R, Bash S, Archer JRH, Eddleston M, Thompson JP, Vale JA, Thomas SHL, Dargan PI. Eur J Hosp Pharm 2015; 23: 145-50.


Increasing frequency of severe clinical toxicity after use of 2,4-dinitrophenol in the UK: a report from the National Poisons Information Service. Kamour A, George N, Gwynnette D, Cooper G, Lupton D, Eddleston M, Thompson JP, Vale JA, Thanacoody HKR, Hill S, Thomas SHL. Emerg Med J 2015; 32: 383-6.


Self-poisoning in the elderly: A 10-year observational study. Morrison EE, Dear JW, Sandilands EA. Clin Toxicol 2015; 53: 404-7.


Disproportionate effect on child admissions of the change in MHRA guidance for management of paracetamol poisoning. Narayan H, Thomas SHL, Eddleston M, Dear JW, Sandilands E, Bateman DN. Br J Clin Pharmacol 2015; 80: 1458-63.


Cost-effectiveness analyses of self-harm strategies aimed at reducing the mortality of pesticide self-poisonings in Sri Lanka: a study protocol. Madsen LB, Eddleston M, Hansen KS, Pearson M, Agampodi S, Jayamanne S, Konradsen F. BMJ Open. 2015 Feb 27;5(2):e007333.


A qualitative study of the relationship between the Scottish Medicines Consortium and their clinical experts. Newham R, Corcoran ED, Dear JW, Hems S, McTaggart S, Bennie M. J Eval Clin Pract. 2015 Mar 23.


Understanding the pathophysiological regulatory role of microRNAs in acute liver failure. Antoine DJ, Dear JW, Goldring CE, Park BK. Hepatology. 2015 Apr;61(4):1439-40.


Life-threatening opioid toxicity from a fantanyl patch applied to eczematous skin. Doris MK, Sandilands EA. BMJ Case Reports 2015 Apr 29. 


Risk factors associated with purchasing pesticide from shops for self-poisoning: a protocol for a population-based case-control study. Weerasinghe M, Konradsen F, Eddleston M, Pearson M, Gunnell D, Hawton K, Jayamanne S, Pabasara C, Jayathilaka T, Dissanayaka K, Rajapaksha S, Thilakarathna P, Agampodi S. BMJ Open. 2015 May 20;5(5):e007822.


Fomepizole versus ethanol in the treatment of acute methanol poisoning: Comparison of clinical effectiveness in a mass poisoning outbreak. Zakharov S, Pelclova D, Navratil T, Belacek J, Komarc M, Eddleston M, Hovda KE. Clin Toxicol (Phila). 2015 Jun;53(8):797-806.


Exosome isolation: a microfluidic road-map. Liga A, Vliegenthart AD, Oosthuyzen W, Dear JW, Kersaudy-Kerhoas M. Lab Chip. 2015 Jun 7;15(11):2388-94.


Paracetamol poisoning: beyond the nomogram. Bateman DN. Br J Clin Pharmacol 2015 Jul; 80 (1):45-50.


Limitations of AST/ALT ratio in paracetamol poisoning. Bateman DN, Dear JW. Clin Toxicol (Phila) 2015 Jul; 53 (6): 580.


Where are we now with paracetamol? Dear JW, Antoine DJ, Park BK. BMJ. 2015 Jul 10;351.


TOXBASE and its use in collecting data on new and uncommon products of interest. Adams RD, Good AM, Thomas SHL, Thompson JP, Vale JA, Eddleston M Clin Toxicol 2015; 53: 398.


Overdoses of riluzole reported to the UK National Poisons Information Service. Good AM, McGrory C, Thomas SHL, Thompson JP, Vale JA, Eddleston M. Clin Toxicol 2015; 53: 385-6.


 Three “toxic” plants. Good AM, McGrory C, Thomas SHL, Thompson JP, Vale JA, Eddleston M. Clin Toxicol 2015; 53: 347-8.


TOXBASE: Its use in answering poison information enquiries in the UK. Jackson G, Good AM, Thomas SHL, Thompson JP, Vale JA, Eddleston M. Clin Toxicol 2015; 53: 398-9.


TOXBASE: Keeping a poisons information database current and meeting UK demand. Jackson G, Lupton DJ, Good AM, Thomas SHL, Thompson JP, Vale JA, Eddleston M. Clin Toxicol 2015; 53: 399.


Antidotes to coumarins, isoniazid, methotrexate and thyroxine, toxins that work via metabolic processes. Bateman DN, Page CB. Br J Clin Pharmacol 2015 Aug 9. 


Circulating Kidney Injury Molecule 1 Predicts Prognosis and Poor Outcome in Patients With Acetaminophen-Induced Liver Injury. Antoine DJ, Sabbisetti VS, Francis B, Jorgensen AL, Craig DG, Simpson KJ, Bonventre JV, Park BK, Dear JW. Hepatology. 2015 Aug;62(2):591-9.


Changing the management of paracetamol poisoning. Bateman DN. Clin Toxicol (Phila) 2015 Sep 1; 37 (9):2135-41.


Pharmacological treatment of organophosphorus insecticide poisoning: the old and the (possible) new. Eddleston M, Chowdhury FR. Br J Clin Pharmacol. 2015 Sep 14.


Target biomarker profile for the clinical management of paracetamol overdose. Vliegenthart AD, Antoine DJ, Dear JW. Br J Clin Pharmacol. 2015 Sep;80(3):351-62.


Comprehensive microRNA profiling in acetaminophen toxicity identifies novel circulating biomarkers for human liver and kidney injury. Vliegenthart AD, Shaffer JM, Clarke JI, Peeters LE, Caporali A, Bateman DN, Wood DM, Dargan PI, Craig DG, Moore JK, Thompson AI, Henderson NC, Webb DJ, Sharkey J, Antoine DJ, Park BK, Bailey MA, Lader E, Simpson KJ, Dear JW. Sci Rep. 2015 Oct 22;5:15501.


Paracetamol (acetaminophen) poisoning. Park BK, Dear JW, Antoine DJ. BMJ Clin Evid. 2015 Oct 19;2015. pii: 2101.


Abnormal pancreatic enzymes and their prognostic role after acute paraquat poisoning. Li Y, Wang M, Gao Y, Yang W, Xu Q, Eddleston M, Li L, Yu X. Sci Rep. 2015 Nov 25;5:17299.


Management of poisoning with ethylene glycol and methanol in the UK: a prospective study conducted by the National Poisons Information Service (NPIS). Thanacoody RH, Gilfillan C, Bradberry SM, Davies J, Jackson G, Vale AJ, Thompson JP, Eddleston M, Thomas SH. Clin Toxicol (Phila). 2015 Nov 23:1-7.


Impact of paraquat regulation on suicide in South Korea. Cha ES, Chang SS, Gunnell D, Eddleston M, Khang YH, Lee WJ. Int J Epidemiol. 2015 Nov 18.


Endocrine-disrupting chemicals and the diabetes epidemic in countries in the WHO South-East Asia region. Gifford R, Siribaddana S, Forbes S, Eddleston M. Lancet Diabetes Endocrinol. 2015 Dec;3(12):925-7.


Disproportionate effect on child admissions of the change in Medicines and Healthcare Products Regulatory Agency guidance for management of paracetamol poisoning: an analysis of hospital admissions for paracetamol overdose in England and Scotland. Narayan H, Thomas SH, Eddleston M, Dear JW, Sandilands E, Nicholas Bateman D. Br J Clin Pharmacol. 2015 Dec;80(6):1458-63.


CSF1 Restores Innate Immunity After Liver Injury in Mice and Serum Levels Indicate Outcomes of Patients With Acute Liver Failure. Stutchfield BM, Antoine DJ, Mackinnon AC, Gow DJ, Bain CC, Hawley CA, Hughes MJ, Francis B, Wojtacha D, Man TY, Dear JW, Devey LR, Mowat AM, Pollard JW, Park BK, Jenkins SJ, Simpson KJ, Hume DA, Wigmore SJ, Forbes SJ. Gastroenterology. 2015 Dec;149(7):1896-1909.e14.