Publications 2016


Assessment of the impact of the Scottish public health campaign on patient reporting of adverse drug reactions. Aldeyab MA, Noble SC, Cuthbert M, Maxwell S, Dear J, Boyter A. Drug Ther Perspect 2016; 32: 209-18.


How to treat paracetamol overdose and when to do it. Antoine DJ, Dear JW. Expert Rev Clin Pharmacol 2016. Published online 2/3/16.


Chorioretinal thinning in chronic kidney disease links to inflammation and endothelial dysfunction. Balmforth C, van Bragt JJMH, Ruijs T, Cameron J, Kimmitt RA, Moorhouse R, Czopek A, Hu MK, Gallacher PJ, Dear JW, Borooah S, MacIntyre IM, Pearson TMC, Willox L, Talwar D, Tafflet M, Roubeix C, Sennlaub F, Chandran S, Dhillon B, Webb DJ, Dhaun N. JCI Insight 2016. Published online 8/12/16.


New regimens for intravenous acetylcysteine, Where are we now? Bateman DN, Dear JW, Thomas SHL. Clin Toxicol 2016; 54: 75-8.


Plasma paracetamol concentration at hospital presentation has a dose-dependent relationship with liver injury despite prompt treatment with intravenous acetylcysteine. Cairney DG, Beckwith HKS, Al-Hourani K, Eddleston M, Bateman DN, Dear JW. Clin Toxicol 2016; 54: 405-10.


Recent advances in biomarkers and therapeutic interventions for hepatic drug safety - false dawn or new horizon? Clarke JI, Dear JW, Antoine DJ. Expert Opin Drug Saf 2016; 25: 625-34.


Glucocorticoids induce nondipping blood pressure by activating the thiazide-sensitive cotransporter. Ivy JR, Oosthuyzen W, Peltz TS, Howarth AR, Hunter RW, Dhaun N, Al-Dujaili EA, Webb DJ, Dear JW, Flatman PW, Bailey MA. Hypertension 2016. Published online 7/3/16.


Central nervous system toxicity of mefenamic acid overdose compared with other NSAIDs: an analysis of cases reported to the United Kingdom National Poisons Information Service. Kamour A, Crichton S, Cooper G, Lupton DJ, Eddleston M, Vale JA, Thompson JP, Thomas SH. Br J Clin Pharmacol 2016; 83: 855-62.


Ethanol consumption produces a small increase in circulating miR-122 in healthy individuals. McCrae JC, Sharkey N, Webb DJ, Vliegenthart AD, Dear JW. Clin Toxicol 2016; 54: 53-5.


Renal extracellular vesicles: from physiology to clinical application. Morrison EE, Bailey MA, Dear JW. J Physiol 2016; 594: 5735-48.


Vasopressin regulates extracellular vesicle uptake by kidney collecting duct cells. Oosthuyzen W, Scullion KM, Ivy JR, Morrison EE, Hunter RW, Starkey Lewis PJ, O'Duibhir E, Street JM, Caporali A, Gregory CD, Forbes SJ, Webb DJ, Bailey MA, Dear JW. J Am Soc Nephrol 2016. Published online 28/3/16.


754 exposures to reed diffusers reported to the United Kingdom National Poisons Information Service 2010-2014. Panchal B, Eddleston M, Thomas SH, Thompson JP, Vale JA. Clin Toxicol 2016; 54: 333-8.


Serum alkalinisation is the cornerstone of treatment for amitriptyline poisoning. Ramasubbu B, James D, Scurr A, Sandilands EA. BMJ Case Reports 2016. Published online 11/4/16.


Taking stock: UK national antidote availability increasing, but further improvements are required. Rehman B, Wind K, Wood DM, Thanacoody R, Bailey GP, Nash S, Archer JRH, Eddleston M, Thompson JP, Vale JA, Thomas SHL, Dargan PI.Eur J Hosp Pharmacy 2016; 23: 145-50.


The effect of renal dysfunction and haemodialysis on circulating liver specific miR-122. Rivoli L, Vliegenthart B, de Potter C, van Bragt J, Tzoumas N, Gallacher P, Farrah TE, Dhaun N, Dear JW. Br J Clin Pharmacol 2016. Published online 21/10/16.


Management of poisoning with ethylene glycol and methanol in the UK: a prospective study conducted by the National Poisons Information Service (NPIS). Thanacoody RHK, Gilfillan C, Bradberry SM, Davies J, Jackson G, Vale JA, Thompson JP, Eddleston M, Thomas SHL. Clin Toxicol 2016; 54: 134-40.


Circulating acetaminophen metabolites are toxicokinetic biomarkers of acute liver injury. Vliegenthart A, Kimmitt RA, Seymour JH, Homer NZ, Clarke JI, Eddleston M, Gray A, Wood DM, Dargan PI, Cooper JG, Antoine DJ, Webb DJ, Lewis SC< Bateman DN, Dear JW. Clin Pharmacol Ther 2016. Published online 22/10/16


The epidemiology of poisoning. Sandilands EA, Bateman DN. Medicine 2016; 44: 76-9.


Paracetamol (acetaminophen). Bateman DN, Vale A. Medicine 2016; 44: 190-2.


Antidepressants. Dear JW, Bateman DN. Medicine 2016; 44: 135-7.


Antipsychotic drugs. Dear JW, Bateman DN. Medicine 2016; 44: 143-4.


Benzodiazepines. Dear JW, Bateman DN. Medicine 2016; 44: 145.


 Iron. Dear JW, Bateman DN. Medicine 2016; 44: 173-4.


Pesticides. Eddleston M. Medicine 2016; 44: 193-6.


Carbon monoxide. Sandilands EA, Bateman DN. Medicine 2016; 44: 151-2.


 Non-steroidal anti-inflammatory drugs. Sandilands EA, Bateman DN. Medicine 2016; 44: 185-6.


Opioids. Sandilands EA, Bateman DN. Medicine 2016; 44: 187-9.